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Jennifer A Quinn Selected Research

O(6)-benzylguanine

10/2009Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
7/2009Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
3/2009Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.
2/2009Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme.
10/2005Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
5/2002Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.

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Jennifer A Quinn Research Topics

Disease

27Glioma (Gliomas)
10/2009 - 03/2002
11Glioblastoma (Glioblastoma Multiforme)
12/2009 - 01/2004
11Neoplasms (Cancer)
12/2009 - 05/2002
4Brain Neoplasms (Brain Tumor)
10/2007 - 09/2005
1Lymphoma (Lymphomas)
08/2013
1Hydrocephalus (Hydrocephaly)
02/2009
1Infections
02/2009
1Medulloblastoma
10/2008
1Turcot syndrome
08/2008
1Hypoglycemia (Reactive Hypoglycemia)
10/2006
1Hyperglycemia
10/2006
1Adenocarcinoma
01/2006
1Astrocytoma (Pilocytic Astrocytoma)
01/2006
1Gliosarcoma
01/2006
1Oligodendroglioma
01/2006
1Diarrhea
01/2004
1Thrombocytopenia (Thrombopenia)
04/2003

Drug/Important Bio-Agent (IBA)

13Temozolomide (Temodar)FDA LinkGeneric
08/2013 - 02/2003
9Irinotecan (Camptosar)FDA LinkGeneric
12/2009 - 04/2004
6O(6)-benzylguanineIBA
10/2009 - 05/2002
6Monoclonal AntibodiesIBA
11/2008 - 03/2002
4Carmustine (FIVB)FDA Link
10/2007 - 05/2002
4Tyrosine Kinase InhibitorsIBA
05/2007 - 01/2004
3O(6)-Methylguanine-DNA MethyltransferaseIBA
12/2009 - 05/2002
3Bevacizumab (Avastin)FDA Link
11/2008 - 02/2007
3Imatinib Mesylate (Gleevec)FDA Link
06/2008 - 12/2005
3Topoisomerase I InhibitorsIBA
10/2005 - 04/2004
2Alkyl and Aryl TransferasesIBA
02/2009 - 10/2006
2poliferprosan 20 drug combination carmustine (Gliadel)FDA Link
02/2009 - 10/2007
2Proteins (Proteins, Gene)FDA Link
08/2008 - 10/2006
2Phosphotransferases (Kinase)IBA
06/2008 - 07/2007
2Hydroxyurea (Hydrea)FDA LinkGeneric
05/2007 - 12/2005
2Adenosine Triphosphate (ATP)IBA
05/2007 - 12/2005
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
05/2007 - 12/2005
2Gefitinib (Iressa)FDA Link
02/2006 - 01/2004
2ErbB Receptors (EGF Receptor)IBA
02/2006 - 01/2004
1Alkylating AgentsIBA
08/2013
1MethyltransferasesIBA
08/2013
1Drug CombinationsIBA
02/2009
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2008
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
06/2008
1tyrosine receptor (receptor, tyrosine)IBA
06/2008
1bcr-abl Fusion ProteinsIBA
06/2008
1Cytotoxins (Cytolysins)IBA
02/2007
1laromustine (VNP40101M)IBA
01/2007
1Insulin (Novolin)FDA Link
10/2006
1Actins (F Actin)IBA
10/2006
1Blood Glucose (Blood Sugar)IBA
10/2006
1Immunoglobulin G (IgG)IBA
06/2006
1(131)I-ch81C6IBA
06/2006
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
02/2006
1Anticonvulsants (Antiepileptic Drugs)IBA
02/2006
1EnzymesIBA
02/2006
1Sirolimus (Rapamycin)FDA Link
02/2006
1TOR Serine-Threonine KinasesIBA
02/2006
1Iodine-125IBA
01/2006
1INO 1001IBA
09/2005
1Poly (ADP-Ribose) Polymerase-1IBA
09/2005
1A-Form DNA (A-DNA)IBA
09/2005
1Celecoxib (Celebrex)FDA Link
01/2005
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2005
1Etoposide (VP 16)FDA LinkGeneric
04/2003

Therapy/Procedure

7Drug Therapy (Chemotherapy)
10/2008 - 04/2003
6Therapeutics
02/2009 - 09/2005
3Radiotherapy
12/2009 - 02/2006
3Salvage Therapy
11/2008 - 02/2007
2Radioimmunotherapy
01/2006 - 09/2005
1Artificial Respiration (Mechanical Ventilation)
10/2006
1Brachytherapy
01/2006